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Finding
relief from your arthritis pain can be essential to living life on your
terms. With one pill a day, CELEBREX can give you the all-day relief you
need to help you get back to your life. It can stop the pain, swelling,
and stiffness of arthritis. CELEBREX was designed to target the source
of joint pain. Just like all other pain medicines, there are risks with
CELEBREX. Get the facts and get a free online consultation to see if
CELEBREX is the best way to treat your pain.
The following information is a summary about Celebrex.
It is not intended to replace a doctor's instructions.
(CELECOXIB)
USES
Celebrex
is a nonsteroidal anti-inflammatory drug (NSAID) known as a COX-2
inhibitor used to relieve the symptoms of osteoarthritis and rheumatoid
arthritis in adults. It may also be used to treat other conditions as
determined by your doctor.
BEFORE USING
Some medicines or medical conditions may interact with Celebrex. Inform
your doctor or pharmacist  of all prescription and over-the-counter
medicine that you are taking. Additional monitoring of your dose or
condition may be needed if you are taking an ACE inhibitor, an
anticoagulant, furosemide, lithium, or fluconazole.
Inform your doctor of any other medical conditions, allergies, or if you
are pregnant or breast-feeding. Contact your doctor or pharmacist if you
have any questions or concerns about taking this medicine.
HOW TO TAKE THIS MEDICATION
The usual dose of Celebrex for osteoarthritis is 200 mg daily or 100 mg
twice daily. While patients with rheumatoid arthritis should start with
these dosages, some patients with rheumatoid arthritis may benefit from
dosage of 200 mg twice daily.
The maximum daily dose should not exceed 200 mg twice daily. Ask your
doctor, nurse, or pharmacist any questions you may have about this
medicine. This medicine may be taken on an empty stomach or with food.
Store this medicine at room temperature between 59 and 86 degrees F (15
and 30 degrees C) in a tightly-closed container, away from heat and
light.
If you miss a does of Celebrex take it as soon as possible. If it is
almost time for your next dose, skip the missed dose and go back to your
regular dosing schedule. DO NOT TAKE TWO DOSES AT ONCE.
SIDE EFFECTS Side
effects that may occur while taking Celebrex include diarrhea,
indigestion, mild stomach pain, gas, nausea, or headache. If they
continue or are bothersome, check with your doctor. CHECK WITH YOUR
DOCTOR AS SOON AS POSSIBLE if you experience skin rash or itching;
unexplained weight gain; bloating or swelling of ankles, feet, or hands;
vomiting material that looks like coffee grounds; blood in stool or
vomit; yellowing of skin or eyes; or unusual fatigue.
CONTACT YOUR DOCTOR IMMEDIATELY if you experience swelling of face,
lips, eyes, throat, or tongue; difficulty swallowing or breathing; or
hoarseness. If you notice other effects not listed above, contact your
doctor, nurse, or pharmacist.
PRECAUTIONS
DO NOT TAKE THIS MEDICINE IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to
aspirin or any medicine containing aspirin or to a nonsteroidal
anti-inflammatory drug (such as Feldene, Motrin, Naprosyn, Clinoril).
DO NOT TAKE THIS MEDICINE IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to
a sulfonamide antibiotic (Septra DS, Bactrim DS, Gantrisin). A severe
reaction includes a severe rash, hives, breathing difficulties, or
dizziness. If you have a question about whether you are allergic to
Celebrex, contact your doctor or pharmacist. If you experience
difficulty breathing; tightness of chest; swelling of eyelids, face, or
lips; or if you develop a rash or hives, tell your doctor immediately.
Do not take any more doses of this medicine unless your doctor tells you
to do so.
DO NOT EXCEED THE RECOMMENDED DOSE or take Celebrex for longer than
prescribed without checking with your doctor. Keep all doctor and
laboratory appointments while you are using this medicine. THIS MEDICINE
MAY CAUSE STOMACH BLEEDING. If you drink alcohol on a daily basis, do
not take this medicine without first discussing it with your doctor.
Alcohol use combined with Celebrex may increase your risk for stomach
bleeding. Before you begin taking any new medicine, either prescription
or over-the-counter, check with your doctor or pharmacist. This includes
any medicines that contain aspirin, ibuprofen, naproxen, or ketoprofen.
FOR WOMEN
If you plan on becoming pregnant, discuss with your doctor the benefits
and risks of using this medicine during pregnancy. It is unknown if this
medicine is excreted in breast milk. DO NOT BREAST-FEED WHILE TAKING
CELEBREX.
OVERDOSE
Do not share this medicine with others for whom it was not prescribed or
use it for other health conditions. KEEP THIS PRODUCT OUT OF THE REACH
OF CHILDREN. If using Celebrex for an extended period of time, obtain
refills before your supply runs out.
STORAGE
Store at room temperature away from sunlight and moisture. KEEP THIS AND
ALL MEDICATIONS OUT OF THE REACH OF CHILDREN.
Celebrex
Approved for Ankylosing Spondylitis
Celebrex - Approved for Ankylosing Spondylitis; Warnings Updated On
Label. Celebrex (celecoxib) has been approved by the U.S. Food and
Drug Administration for relief of the signs and symptoms associated with
ankylosing spondylitis. This latest use of Celebrex is the sixth
approved indication for Celebrex in the United States. The other
indications for Celebrex include the treatment of osteoarthritis, adult
rheumatoid arthritis, acute pain, menstrual pain, and as a treatment for
familial adenomatous polyposis.
Pfizer, the maker of Celebrex, also announced the FDA has finalized the
prescribing instructions, or label, for Celebrex for all approved uses,
including additional warnings about potential cardiovascular and
gastrointestinal risks. Read more news about the Celebrex from Pfizer.
Pfizer - Celebrex News
Pfizer Inc said today that the U.S. Food and Drug Administration has
approved the company's selective COX-2 inhibitor Celebrex (celecoxib)
for the relief of the signs and symptoms associated with ankylosing
spondylitis, a form of arthritis that affects the spine. Celebrex
continues to be an important treatment option for patients suffering
from the pain of osteoarthritis and adult rheumatoid arthritis, acute
pain, menstrual pain, and as a treatment for familial adenomatous
polyposis, a rare condition that leads to colon cancer.
Pfizer has accumulated extensive clinical data relating to Celebrex over
the past ten years involving more than 40,000 patients worldwide. As
expected, the FDA also finalized the prescribing instructions, or label,
for Celebrex for all approved uses, including additional warnings about
potential cardiovascular and gastrointestinal risks. The FDA also will
require similar warnings for other older arthritis treatments like
ibuprofen and naproxen.
Ankylosing spondylitis, which affects over 400,000 Americans, becomes
the sixth approved indication for Celebrex in the United States. Unlike
other forms of arthritis that typically affect older people, ankylosing
spondylitis usually strikes between the ages of 17 and 35. Approximately
as common as rheumatoid arthritis, ankylosing spondylitis also can cause
inflammation, pain and stiffness in other areas of the body such as the
shoulders, knees, hips, ribs, and feet.
"With this new indication, Celebrex offers physicians a new treatment
option for this difficult-to-treat patient population," said Dr. Joseph
Feczko, Pfizer's chief medical officer. "The inflammation associated
with ankylosing spondylitis can cause such severe pain that people who
suffer from this condition—often young men—cannot perform even simple,
everyday activities like walking and may have trouble attending school
or work."
As anticipated, the final label contains a boxed warning of potential
cardiovascular and gastrointestinal risks for Celebrex that will be
consistent with warnings for other prescription pain relievers,
including older, commonly used medicines like ibuprofen and naproxen.
This addition follows a February 2005 meeting of an FDA advisory panel,
which conducted a rigorous scientific review of selective and
non-selective pain relievers. The panel recommended that stronger
warnings be added to all selective COX-2 pain medicines as well as to
the older, non-steroidal anti-inflammatory drugs (NSAIDs) such as
ibuprofen and naproxen. In addition, the panel recommended avoiding
usage of all NSAIDs and Cox-2 selective medicines to treat the acute
pain associated with heart by-pass surgery.
"We have worked closely with the FDA to ensure that Celebrex's label
provides physicians and patients with the information they need to make
the most appropriate and most informed treatment decisions," Dr. Feczko
said.
Buy
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BEFORE USING
Side
effects that may occur while taking Celebrex include diarrhea,
indigestion, mild stomach pain, gas, nausea, or headache. If they
continue or are bothersome, check with your doctor. CHECK WITH YOUR
DOCTOR AS SOON AS POSSIBLE if you experience skin rash or itching;
unexplained weight gain; bloating or swelling of ankles, feet, or hands;
vomiting material that looks like coffee grounds; blood in stool or
vomit; yellowing of skin or eyes; or unusual fatigue. 
Celebrex
Approved for Ankylosing Spondylitis