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Generic Name : Sibutramine hydrochloride.
Common Uses of Meridia
Meridia helps the seriously overweight shed pounds and keep them off. It
is especially recommended for those who in addition to being overweight
have other health problems such as high blood pressure, diabetes, or
high cholesterol. It is used in conjunction with a low-calorie diet.
Meridia works by boosting levels of certain chemical messengers in the
nervoussystem, including serotonin, dopamine, and norepinephrine.
Meridia is indicated for people who need to lose 30
pounds or more depending on height, and should be used in conjunction
with a reduced-calorie diet.
Appetite Suppressant
MERIDIA works by acting on the appetite control center in the brain.
Studies have shown that using MERIDIA, along with a reduced-calorie diet
and exercise, helped patients lose weight and maintain weight loss for
up to two years.1,2
The active ingredient in MERIDIA, sibutramine, works in the area of the
brain that signals the sense of fullness (satiety).1 Meridia does not
suppress appetite, which is your signal to start eating.
Meridia Precautions
If
Meridia gives you an allergic reaction, you won't be able to use it. You
should also avoid Meridia (and certainly don''t need it) if you suffer
from the compulsive dieting disorder known as anorexia nervosa. Do not
combine Meridia with other drugs used to suppress appetite, and do not
use it within 2 weeks of taking a drug classified as an MAO inhibitor,
including the antidepressant medications Marplan, Nardil, and Parnate.
Meridia substantially increases blood pressure or heart
rate in some patients and should not be given to patients with
uncontrolled or poorly controlled hypertension, history of heart
disease, stroke, severe liver or kidney disease, pregnant women or
nursing mothers. Meridia should be used cautiously in patients with a
history of hypertension, glaucoma, seizures, or mild to moderate kidney
disease. All patients being treated with Meridia should see their doctor
as directed for regular monitoring of blood pressure and heart rate.
Meridia Results
The National Institutes of Health advises that diet drugs be taken only
by severely overweight people who need them for health reasons, and only
in combination with lifestyle modifications. For example, one study
found that people taking the weight-loss drug Meridia (sibutramine) who
also received counseling on diet and exercise lost twice as much weight
as those who received either Meridia or counseling alone.
In
the Knoll clinical studies, overweight patients on Meridia and a reduced
calorie diet, in combination with lifestyle modifications, achieved an
average of 5 to 10 percent weight reduction from their initial weight at
various dosage levels. In one 12 month study, patients who took 10 mg of
Meridia daily lost an average of 10 pounds, while those taking 15 mg
daily lost an average of 14 pounds. The average weight loss in people on
only a reduced calorie diet was 3.5 pounds. Study participants lost most
of their weight in the first six months and maintained statistically
significant weight losses for up to a year (Fentress, 33-34). Although
Meridia’s efficacy profile is modest, the drug’s sustained actions are
advantageous since obesity tends to be a chronic condition.
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