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Treat Influenza and Avian Bird Flu H5N1
Virus
 Tamiflu
is a medicine to treat INFLUENZA - the flu. Tamiflu attacks the flu at
its source and stops it from spreading in the body. Purchase
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Tamiflu
is for treating adults with the flu whose
 flu symptoms
started within the last day or two.
OSELTAMIVIR - ORAL (oss-el-TAM-eh-veer)
COMMON BRAND NAME(S): Tamiflu
USES:
This
medication is used to treat illness (symptoms) caused by the flu virus
(influenza). Oseltamivir is also used to prevent the flu (e.g., in
household members exposed to a flu sufferer).
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HOW TO USE:
Take this medication by mouth as directed by your doctor. You may take
this with food or milk to minimize stomach upset. Take it as soon as flu
symptoms appear or as soon as possible after you have been exposed (both
within 48 hours). If you have the flu: Take oseltamivir (Tamiflu) twice
a day for 5 days; once in the morning and once in the evening. Complete
the entire treatment of 10 doses. To prevent the flu: Take oseltamivir (Tamiflu)
once a day for at least 7 days or take it exactly as prescribed by your
doctor. This medication works best when the amount of medicine in your
body is kept at a constant level. Therefore, take this drug at the same
time(s) each day. Take this medication until the full prescribed amount
is finished, even if symptoms improve. Stopping the medication too early
may result in a relapse of the infection. Inform your doctor if your
condition worsens or if new symptoms appear.
SIDE
EFFECTS:
Nausea may occur. If this effect persists or worsens, notify your doctor
promptly. Tell your doctor immediately if you have any of these unlikely
but serious side effects: dizziness, persistent cough. Tell your doctor
immediately if you have any of these very unlikely but serious side
effects: persistent weakness, fever, sore throat. If you notice other
effects not listed above, contact your doctor or pharmacist.
 PRECAUTIONS:
Tell your doctor your medical history, including: allergies, kidney
problems. This drug may make you dizzy or drowsy; use caution engaging
in activities requiring alertness such as driving or using machinery.
Limit alcoholic beverages. This medication should be used only when
clearly needed during pregnancy. Discuss the risks and benefits with
your doctor. It is not known if this drug passes into breast milk.
Consult your doctor before breast-feeding.
Avian Bird Flu Questions and Answers
 A bird flu virus spreading through Asia, and now reported
in the European part of Turkey, has world health authorities warning of
a worldwide pandemic unseen since World War I. The Bush administration
is discussing quarantines and other methods to control its spread should
it arrive in the United States, but for the moment, bird flu remains
only a potential threat.
Some questions and answers on the bird flu:
Q: What is bird flu?
A: The term "bird flu" generally describes one of several influenza
viruses that birds can carry. But several types can also infect humans.
These are different in makeup from the usual human flus.
Q: What are the symptoms of bird flu in humans?
A: They can include typical flu-like symptoms, like fever, cough, sore
throat and muscle aches, as well as eye infections, pneumonia and severe
respiratory illness. At this point, it is believed to have killed at
least 60 people, the majority in Vietnam, since 2002.
Q: How do humans get bird flu?
A: Right now, authorities believe humans primarily get bird flu from
contact with excretions from infected birds, not from other people with
the illness. Common victims are people who handle poultry on farms or at
live markets. There is one known case of it spreading from one person to
another.
Q: Why is bird flu receiving so much attention?
A: A particular type of bird flu, known as H5N1, is seen as a candidate
to cause a global flu pandemic if it mutates into a form capable of
spreading easily from person to person. Because people have not
developed immunity to H5N1, unlike the usual strains of human flu, it
could have more severe effects on a greater number of people.
Q: Is bird flu the only possible source of a flu pandemic?
A: No. A pandemic could break out should any dramatically different new
flu virus emerge. The last century saw three: in 1918, 1957 and 1968.
The 1918 pandemic, caused by a bird flu that jumped to humans, killed at
least 40 million people; the later outbreaks killed far fewer but still
caused widespread disruption.
Fear of a pandemic is also heightened because it has been 37 years since
the last one, and it is thought that new flu strains capable of causing
a pandemic emerge every 30 years or so.
Estimates of the death toll from a new pandemic vary wildly, and depend
on the level of organized response to an outbreak. Ordinary winter flu
kills 36,000 Americans every year.
Q: How can doctors detect bird flu?
A: With a blood test of a person suspected of having it.
Q: Is there a vaccine for bird flu?
A: Yes. French vaccine maker Sanofi-Pasteur has begun production of a
vaccine against H5N1. But researchers have not settled on how large a
dose will ensure protection. The U.S. government has promised to
stockpile $100 million worth of vaccine, but it is unclear how many
doses that will buy - somewhere between 1.7 million and 20 million.
Authorities say their goal is to have 20 million doses on hand.
If bird flu began spreading widely, scientists would have to check
whether that vaccine still would provide protection or a new one would
be needed. Other manufacturers are working to produce experimental
bird-flu vaccines as well.
Q: Is it part of my flu shot this year?
A: No. The yearly flu shot is composed of vaccines for several varieties
of human flu that are expected to be in circulation this winter.
Officials expect at least 71 million doses to be available.
Q: So how do I get vaccinated for the bird flu?
A: At the moment, the public can't. It is likely the government would
control distribution in the event of an outbreak in an effort to manage
its spread.
Q: How is bird flu treated?
A: Two drugs that fight regular flu,
Tamiflu and
Relenza, are thought to
be effective in treating flu caused by H5N1 if administered quickly.
They also may help prevent infection. The government plans to stockpile
tens of millions of
Tamiflu pills, and a smaller supply of the inhaled
drug
Relenza.
Q: Where is bird flu now?
A: Outbreaks of the H5N1 strain have occurred in poultry in several
countries in Asia, and there are fears it is moving across Eurasia. Tens
of millions of birds died from the disease or have been slaughtered to
contain its spread.
Q: When will bird flu reach the United States?
A: It is not known if or when the H5N1 strain will arrive.
Q: What is the U.S. government's plan in case a pandemic flu reaches
the United States?
A: Preparations are ongoing. Beyond stockpiling vaccines and other
drugs, the government is discussing how to stem rioting at vaccine
clinics; when to close schools or enact quarantines; how to keep
gasoline, electricity, food and water supplies running; and how to
manage the economic fallout.
CDC Chief: Bird Flu 'Not Media Hype'
The bird flu news isn't encouraging, the head of the CDC said today.
The comments by CDC Director Julie M. Gerberding, MD, MPH, came at the
opening of the 2006 National Influenza Vaccine Summit meeting of public
health officials and vaccine manufacturers.
Preparation for a flu pandemic is only a small part of the meeting. But
in her opening remarks, Gerberding stressed how seriously the CDC is
taking the threat of a bird flu pandemic.
"This is not media hype. This is a real situation," Gerberding said.
"And at CDC we are very focused on the possibility of pandemic with this
virus or some unexpected virus."
An Evolving Virus
Bird flu — the virus known technically as H5N1 avian influenza — is
evolving. Whether it will necessarily evolve into a pandemic flu virus
depends on whether it gains the power to spread easily from person to
person.
But only one thing is certain: Flu viruses are notoriously
unpredictable.
Tamiflu and Relenza - Bird Flu Treatment
With Tamiflu, also known as oseltamivir, in short supply, some attention
is turning toward Relenza, which is also known as zanamivir. Approved
the same year as Tamiflu, Relenza has been a distant also-ran.
Unlike Tamiflu, which is taken orally, Relenza requires an inhaler.
Within months of Relenza's approval, there were instances of respiratory
problems and fatalities in users who had asthma or other pulmonary
diseases. But some experts say that the inconvenience of an inhaler and
the risk of side effects were minor considerations compared with the
dangers from flu on a wide scale.
Tamiflu Shortages
As concern about a flu pandemic sweeps official Washington, Congress and
the Bush administration are considering spending billions to buy the
influenza drug Tamiflu. But after months of delay, the United States
will now have to wait in line to get the pills.
Had the administration placed a large order just a few months ago,
Roche, Tamiflu's maker, could have delivered much of the supply by next
year, according to sources close to the negotiations in both government
and industry.
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